- Examine randomized block plans
- Examine simplex-lattice designs
- Define evolutionary operations
- Latin Squares
- Graeco-Latin Square Design
- Hyper-Graeco-Latin Square
- Latin Square: is a type of fractional factorial design

Fractional factorials (like Latin and Graeco-Latin Squares) will not allow analysis of interactions. The interactions are confounded with other effects. (Also add to fractional factorial analysis article.)

## Linear & Quadratic Mathematical Models

- http://www.itl.nist.gov/div898/handbook/pri/section1/pri11.htm
- http://www.itl.nist.gov/div898/handbook/pri/section3/pri336.htm

## Balanced & Orthogonal Designs

The word orthogonal means “having right angles”, so I find it helpful to think of Orthogonal design as “Square design”. A design is orthogonal when factors can be evaluated independently of all other factors.

http://www.micquality.com/six_sigma_glossary/balanced_design.htm (Balanced design)

## Fit, Diagnose Model and Center Points

http://www.itl.nist.gov/div898/handbook/pri/section3/pri337.htm (Center point)